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Article

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression.

The Journal of experimental medicine - 18 Oct 2004

Kallies Axel, Hasbold Jhagvaral, Tarlinton David M, Dietrich Wendy, Corcoran Lynn M, Hodgkin Philip D, Nutt Stephen L

Abstract excerpt

Plasma cells comprise a population of terminally differentiated B cells that are dependent on the transcriptional regulator B lymphocyte--induced maturation protein 1 (Blimp-1) for their development. We have introduced a gfp reporter into the Blimp-1 locus and shown that heterozygous mice express the green fluorescent protein in all antibody-secreting cells (ASCs) in vivo and in vitro. In vitro, these cells...

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Source

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Identifiers

PMID: 15492122
DOI: 10.1084/jem.20040973
PMCID: PMC2211847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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