Article
Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.
The Journal of experimental medicine - 21 Feb 2005
Blink Elizabeth J, Light Amanda, Kallies Axel, Nutt Stephen L, Hodgkin Philip D, Tarlinton David M
Abstract excerpt
Immunization with a T cell-dependent antigen elicits production of specific memory B cells and antibody-secreting cells (ASCs). The kinetic and developmental relationships between these populations and the phenotypic forms they and their precursors may take remain unclear. Therefore, we examined the early stages of a primary immune response, focusing on the appearance of antigen-specific B cells in blood. Within...
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