Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recapitulation of the ovum mutant (Om) phenotype and loss of Om locus polarity in cloned mouse embryos.

Biology of reproduction - 1 Feb 2005

Gao Shaorong, Wu Guangming, Han Zhiming, de la Casa-Esperón Elena, Sapienza Carmen, Latham Keith E

Abstract excerpt

The ovum mutant (Om) locus in mice affects early interactions between sperm and egg that in turn affect viability of embryos beyond the morula stage. Crosses of DDK females to males of many other inbred strains are 95% lethal around the morula stage, whereas reciprocal crosses are fully viable. Available data indicate that the early lethality is the result of an interaction between a factor in the ooplasm and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to Cloning, Organism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Lethal

Share to Genotype

Share to Hybrid Cells

Share to Oocytes

Source

Identifiers

PMID: 15483220
DOI: 10.1095/biolreprod.104.035030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recapitulation of the ovum mutant (Om) phenotype and loss of Om locus polarity in cloned mouse embryos.PMID 15483220Read ↗

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.Semantic proximity Read ↗

Modification of survival rate of mouse embryos developing in heterozygous females for ovum mutant gene.Semantic proximity Read ↗

Locating a modifier gene of Ovum mutant through crosses between DDK and C57BL/6J inbred strains in mice.Semantic proximity Read ↗

The maternal DDK syndrome phenotype is determined by modifier genes that are not linked to Om.Semantic proximity Read ↗

Female germline expression of OVO transcription factor bridges Drosophila generations.Semantic proximity Read ↗

Transmission-ratio distortion through F1 females at chromosome 11 loci linked to Om in the mouse DDK syndrome.Semantic proximity Read ↗

Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: establishment of ES cell lines bearing the Omd conditional lethal mutation.Semantic proximity Read ↗

Female germline expression of OVO transcription factor bridges <i>Drosophila</i> generationsSemantic proximity Read ↗

The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11.Semantic proximity Read ↗

The polar-lethal Ovum mutant gene maps to the distal portion of mouse chromosome 11.Semantic proximity Read ↗

Genetic evidence that the ovo locus is involved in Drosophila germ line sex determination.Semantic proximity Read ↗

Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.