Article
The polar-lethal Ovum mutant gene maps to the distal portion of mouse chromosome 11.
Genetics - 1 Sept 1992
Sapienza C, Paquette J, Pannunzio P, Albrechtson S, Morgan K
Abstract excerpt
Genome imprinting is the process by which identical alleles at a particular locus may be rendered functionally different depending on the sex of the parent contributing the allele. While several mutations in imprinted genes have been defined, no variants in the regulatory system that gives rise to imprinting have been described. Here we report our genetic analysis of the behavior of the interstrain, polar,...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Female
- Genes, Lethal
- Genotype
- Infertility, Male
- Litter Size
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains