Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells.

Genetics - 1 Apr 1992

Garfinkel M D, Lohe A R, Mahowald A P

Abstract excerpt

The Drosophila melanogaster ovo gene is required for survival and differentiation of female germline cells, apparently playing a role in germline sex determination. We recovered 60 kb of genomic DNA from its genetic location at 4E1,2 on the X chromosome. A transcription unit coding for an apparently female-specific germline-dependent 5-kb poly(A)+ RNA size class is located substantially in a 7-kb region, within...

Topics

Animals
Chromosome Walking
Cloning, Molecular
Drosophila melanogaster
Genes, Lethal
Germ Cells
Mutation
Poly A
RNA, Messenger
Repetitive Sequences, Nucleic Acid
Sex Determination Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1349870
DOI: 10.1093/genetics/130.4.791
PMCID: PMC1204929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1349870-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells.PMID 1349870Read ↗

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development.Semantic proximity Read ↗

Female germline expression of OVO transcription factor bridges <i>Drosophila</i> generationsSemantic proximity Read ↗

Female germline expression of OVO transcription factor bridges Drosophila generations.Semantic proximity Read ↗

Genetic evidence that the ovo locus is involved in Drosophila germ line sex determination.Semantic proximity Read ↗

Identification of regions interacting with ovoD mutations: potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster.Semantic proximity Read ↗

OVO Positively Regulates Essential Maternal Pathways by Binding Near the Transcriptional Start Sites in the <i>Drosophila</i> Female GermlineSemantic proximity Read ↗

A <i>mdg4</i> Retrotransposon Screen for X-linked Female Sterile Alleles and its Relationship with the Transcription Factor OVOSemantic proximity Read ↗

stand still, a Drosophila gene involved in the female germline for proper survival, sex determination and differentiation.Semantic proximity Read ↗

The role of the ovarian tumor locus in Drosophila melanogaster germ line sex determination.Semantic proximity Read ↗

Gonadal dysgenesis reveals sexual dimorphism in the embryonic germline of Drosophila.Semantic proximity Read ↗

Sex determination signals control ovo-B transcription in Drosophila melanogaster germ cells.Semantic proximity Read ↗

Female germ cells of Drosophila require zygotic ovo and otu product for survival in larvae and pupae respectively.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.