Article
The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11.
Genetics - 1 Jan 2006
Bell Timothy A, de la Casa-Esperón Elena, Doherty Heather E, Ideraabdullah Folami, Kim Kuikwon, Wang Yunfei, Lange Leslie A, Wilhemsen Kirk, Lange Ethan M, Sapienza Carmen, de Villena Fernando Pardo-Manuel
Abstract excerpt
The DDK syndrome is an early embryonic lethal phenotype observed in crosses between females of the DDK inbred mouse strain and many non-DDK males. Lethality results from an incompatibility between a maternal DDK factor and a non-DDK paternal gene, both of which have been mapped to the Ovum mutant (Om) locus on mouse chromosome 11. Here we define a 465-kb candidate interval for the paternal gene by recombinant...
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