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Article

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.

Gene - 21 Aug 2002

Le Bras Stéphanie, Cohen-Tannoudji Michel, Guyot Valérie, Vandormael-Pournin Sandrine, Coumailleau Franck, Babinet Charles, Baldacci Patricia

Abstract excerpt

The DDK syndrome is defined as the embryonic lethality of F1 mouse embryos from crosses between DDK females and males from other strains (named hereafter as non-DDK strains). Genetically controlled by the Ovum mutant (Om) locus, it is due to a deleterious interaction between a maternal factor present in DDK oocytes and the non-DDK paternal pronucleus. Therefore, the DDK syndrome constitutes a unique genetic tool...

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Source

Identifiers

PMID: 12383505
DOI: 10.1016/s0378-1119(02)00832-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.PMID 12383505Read ↗

Recapitulation of the ovum mutant (Om) phenotype and loss of Om locus polarity in cloned mouse embryos.Semantic proximity Read ↗

Locating a modifier gene of Ovum mutant through crosses between DDK and C57BL/6J inbred strains in mice.Semantic proximity Read ↗

Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.Semantic proximity Read ↗

The maternal DDK syndrome phenotype is determined by modifier genes that are not linked to Om.Semantic proximity Read ↗

A <i>mdg4</i> Retrotransposon Screen for X-linked Female Sterile Alleles and its Relationship with the Transcription Factor OVOSemantic proximity Read ↗

Maternal regulation of the vertebrate oocyte-to-egg transitionSemantic proximity Read ↗

Modification of survival rate of mouse embryos developing in heterozygous females for ovum mutant gene.Semantic proximity Read ↗

A mdg4 retrotransposon screen for X-linked female sterile alleles and its relationship with the transcription factor OVO.Semantic proximity Read ↗

Female germline expression of OVO transcription factor bridges <i>Drosophila</i> generationsSemantic proximity Read ↗

The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11.Semantic proximity Read ↗

Maternal regulation of the vertebrate oocyte-to-embryo transition.Semantic proximity Read ↗

OVO Positively Regulates Essential Maternal Pathways by Binding Near the Transcriptional Start Sites in the <i>Drosophila</i> Female GermlineSemantic proximity Read ↗

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