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Article

Female germline expression of OVO transcription factor bridges Drosophila generations.

G3 (Bethesda, Md.) - 5 Feb 2025

Benner Leif, Muron Savannah, Wingfield Charli L, Oliver Brian

Abstract excerpt

OVO is required for female germ cell viability but has no known function in the male germline in Drosophila. ovo is autoregulated by 2 antagonistic isoforms, OVO-A and OVO-B. All ovo- alleles were created as partial revertants of the antimorphic ovoD1 allele. Creation of new targeted alleles in an ovo+ background indicated that disrupting the germline-specific exon extension of ovo-B leads to an arrested egg...

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Identifiers

PMID: 39489490
DOI: 10.1093/g3journal/jkae252
PMCID: PMC11797041

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Female germline expression of OVO transcription factor bridges Drosophila generations.PMID 39489490Read ↗

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