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Article

A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man.

Genes & development - 1 Mar 1992

Falb D, Maniatis T

Abstract excerpt

The Drosophila melanogaster alcohol dehydrogenase (Adh) gene is expressed in a specific set of tissues during larval development and in adults. Expression in the adult fat body is controlled by the Adh adult enhancer (AAE). Previous studies identified a negative regulatory element in the AAE and a protein that binds specifically to this sequence [adult enhancer factor-1 (AEF-1)]. Here, we show that the...

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PMID: 1547943
DOI: 10.1101/gad.6.3.454

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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