Article

Enhanced C/EBPα function extends healthspan and lifespan in the African turquoise killifish

2025-02-23

Abstract excerpt

<h4>ABSTRACT</h4> The transcription factor CCAAT/enhancer binding protein alpha (C/EBPα) regulates cell differentiation, proliferation, and function in various tissues, including the liver, adipose tissue, skin, lung, and hematopoietic system. Studies in rats, mice, humans, and chickens have shown that CEBPA mRNA undergoes alternative translation initiation, producing three C/EBPα protein isoforms. Two of these i...

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Literature Corpus work: ff23b4d9-d141-5f7f-a786-e37c08555da0
DOI: 10.1101/2025.02.18.638802

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