Article
Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression.
DNA and cell biology - 1 Apr 1998
Li M, Edenberg H J
Abstract excerpt
The ADH4 gene, which encodes human pi-alcohol dehydrogenase, is expressed in a tissue-specific manner, with the highest level in liver and lower levels in the gastrointestinal tract. We examined the location and function of the cis-acting elements that regulate ADH4 transcription. Liver contains proteins that bound to seven sites in the proximal promoter (from bp -387 to bp +17). Proteins from other tissues bound...
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