Article
Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression.
DNA and cell biology - 1 Apr 1998
Li M, Edenberg H J
Abstract excerpt
The ADH4 gene, which encodes human pi-alcohol dehydrogenase, is expressed in a tissue-specific manner, with the highest level in liver and lower levels in the gastrointestinal tract. We examined the location and function of the cis-acting elements that regulate ADH4 transcription. Liver contains...
Topics
- Alcohol Dehydrogenase
- Animals
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- Carcinoma, Hepatocellular
- Cell Extracts
- Cell Line
- Chlorocebus aethiops
- DNA
- DNA Methylation
- DNA-Binding Proteins
- Gene Expression Regulation, Enzymologic
- Humans
- Kidney
- Liver
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data