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Article

Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations.

Clinical pharmacology and therapeutics - 1 Sept 2006

Nakajima Miki, Fukami Tatsuki, Yamanaka Hiroyuki, Higashi Eriko, Sakai Haruko, Yoshida Ryoko, Kwon Jun-Tack, McLeod Howard L, Yokoi Tsuyoshi

Abstract excerpt

Human cytochrome P450 (CYP) 2A6 metabolizes nicotine to cotinine and is a possible modulator of nicotine addiction. Quantitative and qualitative differences in nicotine addiction have been observed between ethnic groups. However, there are few data on the ethnic influences of the CYP2A6-nicotine metabolism relationship, particularly with regard to black subjects. We determined the nicotine metabolism and CYP2A6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16952495
DOI: 10.1016/j.clpt.2006.05.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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