Article
Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene.
Pharmacogenetics - 1 Sept 2004
Wu Michael H, Chen Peixian, Wu Xiaolin, Liu Wanqing, Strom Stephen, Das Soma, Cook Edwin H, Rosner Gary L, Dolan M Eileen
Abstract excerpt
Carboxylesterases are members of the serine esterase super family important in the metabolism of a wide variety of substrates, including xenobiotics and prodrugs. There are two known carboxylesterases expressed in human liver, small intestine and other tissues, carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2). The aim of this study was to identify polymorphisms in the CES2 gene and determine whether these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.