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Article

Interleukin-10 knockout mouse: a model for studying bone metabolism during intestinal inflammation.

Inflammatory bowel diseases - 1 Sept 2004

Cohen Stacey L, Moore Aideen M, Ward Wendy E

Abstract excerpt

The objective was to compare bone mass (bone mineral content [BMC], bone mineral density [BMD]) and biomechanical strength of femurs and lumbar vertebrae from male and female wild-type (WT) and IL-10 knockout (KO) mice to determine if the IL-10 KO mouse model is appropriate for studying inflammation-associated bone abnormalities and potential interventions. Offspring from IL-10 KO and WT mice (n = 15 to 19...

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PMID: 15472515
DOI: 10.1097/00054725-200409000-00009

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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