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Article

Bone abnormalities in adolescent leptin-deficient mice.

Regulatory peptides - 11 Sept 2006

Ealey Kafi N, Fonseca Debbie, Archer Michael C, Ward Wendy E

Abstract excerpt

Ob/ob and db/db mice have different aberrations in leptin signaling that both lead to abnormalities in bone mineral density (BMD), and bone histological and histomorphometric outcomes. A few studies have directly compared bone metabolism in ob/ob and db/db mice, and biomechanical strength properties that are surrogate measures of fracture risk, have not been extensively studied. This study compared bone mineral...

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Identifiers

PMID: 16764953
DOI: 10.1016/j.regpep.2006.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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