Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging.

Abstract excerpt

Osteoporosis results from impaired bone remodeling and deterioration of bone microarchitecture, ultimately increasing fracture risk. Although early-life nutritional stress has been implicated in long-term health outcomes, its impact on skeletal remodeling mechanisms remains unclear. We investigated whether gestational protein restriction induces persistent alterations in the skeletal immune microenvironment that...

Topics

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• Aging
• Bone and Bones
• Bone Density
• Bone Remodeling
• Diet, Protein-Restricted