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Article

Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord.

Development (Cambridge, England) - 1 Nov 2004

Wine-Lee Lara, Ahn Kyung J, Richardson Rory D, Mishina Yuji, Lyons Karen M, Crenshaw E Bryan

Abstract excerpt

During spinal cord development, distinct classes of interneurons arise at stereotypical locations along the dorsoventral axis. In this paper, we demonstrate that signaling through bone morphogenetic protein (BMP) type 1 receptors is required for the formation of two populations of commissural neurons, DI1 and DI2, that arise within the dorsal neural tube. We have generated a double knockout of both BMP type 1...

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Source

Identifiers

PMID: 15469980
DOI: 10.1242/dev.01379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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