Article
Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.
Development (Cambridge, England) - 1 Mar 2005
Murali Deepa, Yoshikawa Shunichi, Corrigan Rebecca R, Plas Daniel J, Crair Michael C, Oliver Guillermo, Lyons Karen M, Mishina Yuji, Furuta Yasuhide
Abstract excerpt
The Bmp family of secreted signaling molecules is implicated in multiple aspects of embryonic development. However, the cell-type-specific requirements for this signaling pathway are often obscure in the context of complex embryonic tissue interactions. To define the cell-autonomous requirements for Bmp signaling, we have used a Cre-loxP strategy to delete Bmp receptor function specifically within the developing...
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