Article
BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Jul 2007
Samanta Jayshree, Burke Gordon M, McGuire Tammy, Pisarek Anna J, Mukhopadhyay Abhishek, Mishina Yuji, Kessler John A
Abstract excerpt
Progenitor cells that express the transcription factor olig1 generate several neural cell types including oligodendrocytes and GABAergic interneurons in the dorsal cortex. The fate of these progenitor cells is regulated by a number of signals including bone morphogenetic proteins (BMPs) secreted in the dorsal forebrain. BMPs signal by binding to heteromeric serine-threonine kinase receptors formed by type I...
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