Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.

doi:10.1101/gad.12.21.3394

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Article

Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.

Genes & development - 1 Nov 1998

Lee K J, Mendelsohn M, Jessell T M

Abstract excerpt

Inductive factors are known to direct the regional differentiation of the vertebrate central nervous system (CNS) but their role in the specification of individual neuronal cell types is less clear. We have examined the function of GDF7, a BMP family member expressed selectively by roof plate cel...

Topics

Amino Acid Sequence
Animals
Basic Helix-Loop-Helix Transcription Factors
Body Patterning
Bone Morphogenetic Proteins
Chick Embryo
Embryonic Induction
Growth Differentiation Factors
Growth Plate
Growth Substances
Homeodomain Proteins
Humans
Interneurons
LIM-Homeodomain Proteins
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 9808626
DOI: 10.1101/gad.12.21.3394
PMCID: PMC317230

Genes

GDF7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9808626-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

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Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.