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Article

Nuclear export signal in CDC25B.

Biochemical and biophysical research communications - 26 Mar 2004

Uchida Sanae, Ohtsubo Motoaki, Shimura Mari, Hirata Masato, Nakagama Hitoshi, Matsunaga Tsukasa, Yoshida Minoru, Ishizaka Yukihito, Yamashita Katsumi

Abstract excerpt

CDC25B is a dual-specificity phosphatase that activates CDK1/cyclin B. The nuclear exclusion of CDC25B is controlled by the binding of 14-3-3 to the nuclear export signal (NES) of CDC25B, which was reported to be amino acids H28 to L40 in the N-terminal region of CDC25B. In studying the subcellular localization of CDC25B, we found a functional NES at V52 to L65, the sequence of which is VTTLTQTMHDLAGL, where bold...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15003534
DOI: 10.1016/j.bbrc.2004.02.039

Genes

NES
CDK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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