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Article

Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis.

The Journal of cell biology - 9 Aug 1999

Karlsson C, Katich S, Hagting A, Hoffmann I, Pines J

Abstract excerpt

We have used time-lapse fluorescence microscopy to study the properties of the Cdc25B and Cdc25C phosphatases that have both been implicated as initiators of mitosis in human cells. To differentiate between the functions of the two proteins, we have microinjected expression constructs encoding Cdc25B or Cdc25C or their GFP-chimeras into synchronized tissue culture cells. This assay allows us to express the...

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Identifiers

PMID: 10444066
DOI: 10.1083/jcb.146.3.573
PMCID: PMC2150562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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