Article
Analysis of the role of phosphorylation in fission yeast Cdc13p/cyclinB function.
The Journal of biological chemistry - 15 Apr 2005
Ren Liping, Feoktistova Anna, McDonald W Hayes, Haese Greg Den, Morrell Jennifer L, Gould Kathleen L
Abstract excerpt
The Cdk1p-cyclin B complex drives entry into mitosis in all eukaryotes. Cdc13p is the single essential cyclin in Schizosaccharomyces pombe and a member of the cyclin B family. Cdc13p abundance rises during G(2)-phase and falls as cells progress through mitosis and G(1). Cdc13p degradation, mediated by the anaphase-promoting complex, is an important mechanism of Cdk1p inhibition and mitotic exit. Cdk1p-cyclin B1...
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