Article
Major histocompatibility complex class I core promoter elements are not essential for transcription in vivo.
Molecular and cellular biology - 1 Nov 2013
Barbash Zohar S, Weissman Jocelyn D, Campbell John A, Mu Jie, Singer Dinah S
Abstract excerpt
The role of core promoter elements in regulating transcription initiation is largely unknown for genes subject to complex regulation. Major histocompatibility complex class I genes are ubiquitously expressed and governed by tissue-specific and hormonal signals. Transcription initiates at multiple sites within the core promoter, which contains elements homologous to the canonical elements CCAAT, TATAA, Sp1 binding...
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