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Article

Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.

Circulation research - 1 Aug 1993

Bassel-Duby R, Grohe C M, Jessen M E, Parsons W J, Richardson J A, Chao R, Grayson J, Ring W S, Williams R S

Abstract excerpt

To define sequence elements required for myoglobin gene transcription in the intact heart, we examined the expression of a reporter gene under the control of a 380-bp upstream segment (-373 to +7) from the human myoglobin gene in transgenic mouse embryos and after gene transfer into left ventricular myocardium of adult rats. This proximal upstream region was sufficient to direct expression of luciferase...

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Identifiers

PMID: 8330378
DOI: 10.1161/01.res.73.2.360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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