Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.

doi:10.1161/01.res.73.2.360

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Article

Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.

Circulation research - 1 Aug 1993

Bassel-Duby R, Grohe C M, Jessen M E, Parsons W J, Richardson J A, Chao R, Grayson J, Ring W S, Williams R S

Abstract excerpt

To define sequence elements required for myoglobin gene transcription in the intact heart, we examined the expression of a reporter gene under the control of a 380-bp upstream segment (-373 to +7) from the human myoglobin gene in transgenic mouse embryos and after gene transfer into left ventricu...

Topics

Animals
Base Sequence
Heart
Heart Ventricles
Humans
Mice
Mice, Inbred Strains
Mice, Transgenic
Molecular Sequence Data
Mutation
Myoglobin
Oocytes
Promoter Regions, Genetic
Rats
Rats, Sprague-Dawley
Transcription, Genetic
Transfection

Source

Open in PubMed

Identifiers

PMID: 8330378
DOI: 10.1161/01.res.73.2.360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8330378-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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