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Article

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression.

The EMBO journal - 1 Jan 1990

Collis P, Antoniou M, Grosveld F

Abstract excerpt

The human beta-globin dominant control region (DCR) was previously identified as a region from the 5' end of the human beta-globin locus which directs high level, site of integration-independent, copy number-dependent expression on a linked human beta-globin gene in transgenic mice and stably transfected mouse erythroleukaemia (MEL) cells. We have now analysed the elements comprising the DCR by systematic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2295312
DOI: 10.1002/j.1460-2075.1990.tb08100.x
PMCID: PMC551652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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