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Article

Identification of Essential GATA and Ets Binding Motifs within the Promoter of the Platelet Glycoprotein Ibα Gene

1 Oct 1995

Abstract excerpt

Platelet glycoprotein (GP) Ib-IX-V is a multisubunit adhesion receptor that supports platelet attachment to thrombogenic surfaces at sites of vascular injury. The congenital absence of the receptor results in a bleeding disorder associated with "giant" platelets, a condition linking the expression of the complex to platelet morphogenesis. To understand better the expression of the GP Ib-IX-V complex, studies were...

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Identifiers

PMID: 7592671
DOI: 10.1074/jbc.270.41.24532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Essential GATA and Ets Binding Motifs within the Promoter of the Platelet Glycoprotein Ibα GenePMID 7592671Read ↗

Identification of a mutation in a GATA binding site of the platelet glycoprotein Ibbeta promoter resulting in the Bernard-Soulier syndrome.Semantic proximity Read ↗

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome.Semantic proximity Read ↗

A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.Semantic proximity Read ↗

Regulation of the Megakaryocytic Glycoprotein IX Promoter by the Oncogenic Ets Transcription Factor Fli-1Semantic proximity Read ↗

Transcription factors in megakaryocytes and plateletsSemantic proximity Read ↗

The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer.Semantic proximity Read ↗

Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein IbαSemantic proximity Read ↗

Platelet defects in congenital variant of Rett syndrome patients with FOXG1 mutations or reduced expression due to a position effect at 14q12.Semantic proximity Read ↗

Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competition.Semantic proximity Read ↗

Characterization of the Human Platelet/Endothelial Cell Adhesion Molecule-1 Promoter: Identification of a GATA-2 Binding Element Required for Optimal Transcriptional ActivitySemantic proximity Read ↗

Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease.Semantic proximity Read ↗

Organization of the gene for platelet glycoprotein IIb.Semantic proximity Read ↗

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