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Human PTIP Facilitates ATM-mediated Activation of p53 and Promotes Cellular Resistance to Ionizing Radiation

29 Sept 2004

Abstract excerpt

Mus musculus Pax2 transactivation domain-interacting protein (Ptip) is an essential gene required for the maintenance of genome stability, although its precise molecular role is unclear. Human PTIP (hPTIP) was recently isolated in a screen for proteins, translated from cDNA pools, capable of interacting with peptides phosphorylated by the ATM (ataxia telangiectasia-mutated)/ATR (ataxia telangiectasia-related)...

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Identifiers

PMID: 15456759
DOI: 10.1074/jbc.m411021200

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Human PTIP Facilitates ATM-mediated Activation of p53 and Promotes Cellular Resistance to Ionizing RadiationPMID 15456759Read ↗

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