Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the translationally controlled tumor protein in DNA damage sensing and repair

26 Mar 2012

Abstract excerpt

The translationally controlled tumor protein (TCTP) is essential for survival by mechanisms that as yet are incompletely defined. Here we describe an important role of TCTP in response to DNA damage. Upon exposure of normal human cells to low-dose γ rays, the TCTP protein level was greatly increased, with a significant enrichment in nuclei. TCTP up-regulation occurred in a manner dependent on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22451927
DOI: 10.1073/pnas.1106300109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the translationally controlled tumor protein in DNA damage sensing and repairPMID 22451927Read ↗

TCTP directly regulates ATM activity to control genome stability and organ development in Drosophila melanogaster.Semantic proximity Read ↗

Influence of Nucleoshuttling of the ATM Protein in the Healthy Tissues Response to Radiation Therapy: Toward a Molecular Classification of Human RadiosensitivitySemantic proximity Read ↗

Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer CellsSemantic proximity Read ↗

Cancer Cells Upregulate Tau to Gain Resistance to DNA Damaging AgentsSemantic proximity Read ↗

A Novel Protein Complex Distinct from Mismatch Repair Binds Thioguanylated DNASemantic proximity Read ↗

TEAD is required for DNA repair independent of its transcriptional functionSemantic proximity Read ↗

Replication stress and FOXM1 drive radiation induced genomic instability and cell transformationSemantic proximity Read ↗

Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells.Semantic proximity Read ↗

Telomere-Binding Protein TPP1 Modulates Telomere Homeostasis and Confers Radioresistance to Human Colorectal Cancer CellsSemantic proximity Read ↗

Exploring the Role of p53 in Radiosensitivity: A Key Player in Cancer TherapySemantic proximity Read ↗

Exploring the Role of p53 in Radiosensitivity: A Key Player in Cancer TherapySemantic proximity Read ↗

DNA damage-induced phosphorylation of the human telomere-associated protein TRF2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.