Article

TRAIP regulates DNA double-strand break-induced ATM activation

2021-10-12

Abstract excerpt

<h4>ABSTRACT</h4> DNA double-strand breaks (DSBs) affect cell survival and genomic integrity. They are repaired by a highly coordinated process called the DNA damage response. Here, we report that the ubiquitously expressed nucleolar E3 ubiquitin ligase TRAF-interacting protein (TRAIP), previously shown to regulate the spindle assembly checkpoint, has an essential role during the DNA damage response. A biotinylat...

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Literature Corpus work: 63019d0b-8916-56d0-9bc3-357682a5c928
DOI: 10.1101/2021.10.11.462297

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