Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat.

doi:10.1385/1-59259-836-6:049

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Article

Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat.

Methods in molecular medicine - 1 Jan 2005

Carswell Hilary V O, McBride Martin W, Graham Delyth, Dominiczak Anna F, Macrae I Mhairi

Abstract excerpt

The recent completion of the Human Genome Project provides the potential to advance our knowledge of pathogenesis and identify the gene(s) associated with particular diseases. However, using human DNA to correlate individual genomic variations with particular disorders such as stroke will be extremely challenging because of the large number of variables within an individual, and across different populations....

Topics

Animals
Crosses, Genetic
Disease Models, Animal
Female
Gene Expression
Humans
Infarction, Middle Cerebral Artery
Male
Microsatellite Repeats
Phenotype
Polymerase Chain Reaction
Quantitative Trait Loci
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Rats, Mutant Strains
Stroke

Source

Open in PubMed

Identifiers

PMID: 15454664
DOI: 10.1385/1-59259-836-6:049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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