Article
Modification of stroke susceptibility by genotype-dependent maternal influences.
Stroke - 1 Nov 1990
Blizard D A, Challa V R, Iskandar S S, el-Tamawy M S, Adams N
Abstract excerpt
The influence of the prenatal and postnatal maternal environment on stroke susceptibility was evaluated by reciprocally crossing the spontaneously hypertensive (SHR) and the Dahl salt-sensitive (SS/Jr) inbred rat strains to produce reciprocal F1 hybrids that were nurtured, respectively, during prenatal and postnatal life by SHR or SS/Jr mothers. Following placement on a high-salt diet containing 8% NaCl at 35...
Topics
- Animals
- Blood Pressure
- Body Weight
- Cerebrovascular Disorders
- Disease Susceptibility
- Female
- Genotype
- Hypertension
- Rats
- Rats, Inbred SHR
- Rats, Inbred Strains
