Congenic/consomic models of hypertension.

Abstract excerpt

Human essential hypertension is a complex, multifactorial, quantitative trait under polygenic control. Despite major recent advances in genome sequencing and statistical tools, the genetic dissection of essential hypertension still provides a formidable challenge. Genetic models of essential hypertension such as the spontaneously hypertensive stroke-prone rat (SHRSP) provide the scientist with genetic...

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