Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotypes of Stim1 and the proximal region on chromosome 1 exert opposite effects on stroke susceptibility in stroke-prone spontaneously hypertensive rat.

Journal of hypertension - 1 Jan 2024

Ohara Hiroki, Takeuchi Fumihiko, Kato Norihiro, Nabika Toru

Abstract excerpt

BACKGROUND: The stroke-prone spontaneously hypertensive rat (SHRSP) is a genetic model for cerebral stroke. Although a recent study on a congenic SHRSP suggested that a nonsense mutation in stromal interaction molecule 1 ( Stim1 ) encoding a major component of store-operated Ca 2+ entry was a causal variant for stroke in SHRSP, this was not conclusive because the congenic region including Stim1 in that rat was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 1
Share to Codon, Nonsense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Share to Stroke

Share to Stromal Interaction Molecule 1

Source

Identifiers

PMID: 37711097
DOI: 10.1097/HJH.0000000000003566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotypes of Stim1 and the proximal region on chromosome 1 exert opposite effects on stroke susceptibility in stroke-prone spontaneously hypertensive rat.PMID 37711097Read ↗

Identification of Stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

Pathophysiological significance of Stim1 mutation in sympathetic response to stress and cardiovascular phenotypes in SHRSP/Izm: In vivo evaluation by creation of a novel gene knock-in rat using CRISPR/Cas9.Semantic proximity Read ↗

Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat.Semantic proximity Read ↗

The stroke-prone spontaneously hypertensive rat: still a useful model for post-GWAS genetic studies?Semantic proximity Read ↗

Mutant animal models of stroke and gene expression: the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

A nonsense mutation of Stim1 identified in stroke-prone spontaneously hypertensive rats decreased the store-operated calcium entry in astrocytesSemantic proximity Read ↗

Reciprocal congenic lines for a major stroke QTL on rat chromosome 1.Semantic proximity Read ↗

Modulation of STIM1 by a risk insertion/deletion polymorphism underlying genetics susceptibility to sudden cardiac death originated from coronary artery disease.Semantic proximity Read ↗

Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.Semantic proximity Read ↗

Single nucleotide polymorphisms in the non-coding region of STIM1 gene are associated with Parkinson disease risk in Chinese Han population.Semantic proximity Read ↗

Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension.Semantic proximity Read ↗

Identification of Noncoding Functional Regulatory Variants of STIM1 Gene in Idiopathic Pulmonary Arterial Hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.