Article
Genes encoding atrial and brain natriuretic peptides as candidates for sensitivity to brain ischemia in stroke-prone hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
Brosnan M J, Clark J S, Jeffs B, Negrin C D, Van Vooren P, Arribas S M, Carswell H, Aitman T J, Szpirer C, Macrae I M, Dominiczak A F
Abstract excerpt
-Previous studies suggested that atrial natriuretic peptide gene (Anp) and brain natriuretic peptide gene (Bnp) are plausible candidate genes for susceptibility to stroke and for sensitivity to brain ischemia in the stroke-prone spontaneously hypertensive rat (SHRSP). We performed structural and...
Topics
- Amino Acid Substitution
- Animals
- Atrial Natriuretic Factor
- Base Sequence
- Brain
- Brain Ischemia
- Cells, Cultured
- Cerebrovascular Disorders
- Chromosome Mapping
- DNA Primers
- Exons
- Genetic Markers
- Genetic Predisposition to Disease
- Hypertension
