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Article

Genetic models of hypertension in experimental animals.

Experimental nephrology - 1 Jan 2001

Yagil Y, Yagil C

Abstract excerpt

Genetic animal models are central to ongoing efforts to elucidate the pathophysiology and genetic basis of hypertension. The rat is the leading species in experimental hypertension. Several rat models of hypertension are available for research, including inbred strains, congenic lines, transgenic animals and recombinant inbred strains. Each of these models has been designed to express different phenotypes,...

Topics

Animals
Animals, Genetically Modified
Blood Pressure Determination
Chromosome Mapping
Disease Models, Animal
Gene Expression
Genetic Techniques
Hypertension
Pedigree
Phenotype
Rats
Rats, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11053974
DOI: 10.1159/000020701

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