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Article

Xin repeats define a novel actin-binding motif.

Journal of cell science - 15 Oct 2004

Pacholsky Dirk, Vakeel Padmanabhan, Himmel Mirko, Löwe Thomas, Stradal Theresia, Rottner Klemens, Fürst Dieter O, van der Ven Peter F M

Abstract excerpt

Xin is a protein that is expressed during early developmental stages of cardiac and skeletal muscles. Immunolocalization studies indicated a peripheral localization in embryonic mouse heart, where Xin localizes with beta-catenin and N-cadherin. In adult tissues, Xin is found primarily in the intercalated discs of cardiomyocytes and the myotendinous junctions of skeletal muscle cells, both specialized attachment...

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Identifiers

PMID: 15454575
DOI: 10.1242/jcs.01406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Xin repeats define a novel actin-binding motif.PMID 15454575Read ↗

New insights into the roles of Xin repeat-containing proteins in cardiac development, function, and disease.Semantic proximity Read ↗

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Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart.Semantic proximity Read ↗

Myomaxin Is a Novel Transcriptional Target of MEF2A That Encodes a Xin-related α-Actinin-interacting ProteinSemantic proximity Read ↗

Intercalated disc protein, mXinα, suppresses p120-catenin-induced branching phenotype via its interactions with p120-catenin and cortactin.Semantic proximity Read ↗

Differences in binding preferences for XIST partners are observed in mammals with different early pregnancy morphologiesSemantic proximity Read ↗

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