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Article

PRR14 mediates mechanotransduction and regulates myofiber identity via MEF2C in skeletal muscle.

Metabolism: clinical and experimental - 1 Mar 2025

Yang Mei, Wang Jiajie, Liu Zhongyue, Li Zhihong

Abstract excerpt

Skeletal muscle is a crucial tissue for physical activity and energy metabolism. Muscle atrophy, characterized by the loss of muscle mass and strength, contributes to adverse outcomes among individuals. This study elucidated the involvement of the nuclear lamina component PRR14 in transmitting mechanical signals and mediating the impact of exercise on skeletal muscle. The expression of PRR14 demonstrated a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39706290
DOI: 10.1016/j.metabol.2024.156109

Genes

PRR14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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