Article

Differences in binding preferences for XIST partners are observed in mammals with different early pregnancy morphologies

2023-10-06

Abstract excerpt

<h4>ABSTRACT</h4> In comparison to protein-coding genes, long non-coding RNAs (lncRNAs) are poorly conserved between species at the sequence level yet they often perform conserved and essential regulatory roles. The lncRNA XIST mediates X chromosome inactivation (XCI) through the interaction of numerous proteins, most of which bind to its repeat regions. Whilst XIST is present across placental mammals, its sequ...

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Literature Corpus work: 97cbea9f-c7b3-5be1-b408-601dff7dcd4f
DOI: 10.1101/2023.10.04.560814

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