Article
New insights into the roles of Xin repeat-containing proteins in cardiac development, function, and disease.
International review of cell and molecular biology - 1 Jan 2014
Wang Qinchuan, Lin Jenny Li-Chun, Erives Albert J, Lin Cheng-I, Lin Jim Jung-Ching
Abstract excerpt
Since the discovery of Xin repeat-containing proteins in 1996, the importance of Xin proteins in muscle development, function, regeneration, and disease has been continuously implicated. Most Xin proteins are localized to myotendinous junctions of the skeletal muscle and also to intercalated discs (ICDs) of the heart. The Xin gene is only found in vertebrates, which are characterized by a true chambered heart....
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