Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of microsatellite instability in children treated for acute lymphocytic leukemia with elevated HPRT mutant frequencies.

Mutagenesis - 1 Sept 2004

Kendall Heather E, Vacek Pamela M, Finette Barry A

Abstract excerpt

Survival rates of children treated for cancer have increased dramatically over the last 25 years following the development of risk-directed multi-modality treatment protocols. As a result, there is a rapidly growing population of children and young adult cancer survivors in which the long-term genotoxic effects of chemotherapeutic intervention is unknown. We have previously observed that children treated for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to Genes, Reporter
Share to Hypoxanthine Phosphoribosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Infant, Newborn

Share to Microsatellite Repeats

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Recurrence

Source

Identifiers

PMID: 15388815
DOI: 10.1093/mutage/geh050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of microsatellite instability in children treated for acute lymphocytic leukemia with elevated HPRT mutant frequencies.PMID 15388815Read ↗

Analysis of genetic alterations and clonal proliferation in children treated for acute lymphocytic leukemia.Semantic proximity Read ↗

Genotoxicity of therapeutic intervention in children with acute lymphocytic leukemia.Semantic proximity Read ↗

Emergence of genetic instability in children treated for leukemia.Semantic proximity Read ↗

Analysis of hprt gene mutation following anti-cancer treatment in pediatric patients with acute leukemia.Semantic proximity Read ↗

Biomarkers in long survivors of pediatric acute lymphoblastic leukemia patients: late effects of cancer chemotherapy.Semantic proximity Read ↗

Comparative analysis of HPRT mutant frequency in children with cancer.Semantic proximity Read ↗

Accumulation of somatic mutations in proliferating T cell clones from children treated for leukemia.Semantic proximity Read ↗

Distinct mechanisms lead to HPRT gene mutations in leukemic cells.Semantic proximity Read ↗

Microsatellite instability occurs in defined subsets of patients with acute myeloblastic leukaemia.Semantic proximity Read ↗

Analysis of mutagenic V(D)J recombinase mediated mutations at the HPRT locus as an in vivo model for studying rearrangements with leukemogenic potential in children.Semantic proximity Read ↗

Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene InactivationSemantic proximity Read ↗

Evaluation of mutant frequencies at the hprt and the T-cell receptor loci in pediatric cancer patients before treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.