Article
Biomarkers in long survivors of pediatric acute lymphoblastic leukemia patients: late effects of cancer chemotherapy.
Mutation research - 3 Dec 1998
Koishi S, Kubota M, Sawada M, Hirota H, Hashimoto H, Lin Y W, Watanabe K, Usami I, Akiyama Y, Furusho K
Abstract excerpt
In order to elucidate the late effects of cancer chemotherapy, mutant frequencies (Mfs) at the hypoxanthine phosphoribosyl transferase (hprt) locus were evaluated in pediatric patients with early pre-B acute lymphoblastic leukemia (ALL). Hprt-Mfs were measured at least 2 years after completion of...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Clone Cells
- Female
- Gene Frequency
- Gene Rearrangement, T-Lymphocyte
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Infant
- Male
- Mutation
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Receptors, Antigen, T-Cell
- Sister Chromatid Exchange
- Time Factors
- fas Receptor