Comparative analysis of HPRT mutant frequency in children with cancer.

doi:10.1002/em.10171

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Article

Comparative analysis of HPRT mutant frequency in children with cancer.

Environmental and molecular mutagenesis - 1 Jan 2003

Rice Sederick C, Vacek Pamela M, Homans Alan H, Kendall Heather, Rivers Jami, Messier Terri, Finette Barry A

Abstract excerpt

The link between exposure to environmental mutagens and the development of cancer is well established. Yet there is a paucity of data on the relationship between gene-environment interactions and the mechanisms associated with the somatic mutational events involved with malignant transformation, especially in children. To gain insight into somatic mutational mechanisms in children who develop cancer, we...

Topics

Adolescent
Age Factors
Child
Child, Preschool
Female
Genetic Markers
Humans
Hypoxanthine Phosphoribosyltransferase
Infant
Male
Mutation
Neoplasms

Source

Open in PubMed

Identifiers

PMID: 12874812
DOI: 10.1002/em.10171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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