Evaluation of mutant frequencies at the hprt and the T-cell receptor loci in pediatric cancer patients before treatment.

doi:10.1016/s0027-5107(97)00233-9

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Article

Evaluation of mutant frequencies at the hprt and the T-cell receptor loci in pediatric cancer patients before treatment.

Mutation research - 2 Feb 1998

Sawada M, Kubota M, Lin Y W, Watanabe K, Koishi S, Usami I, Akiyama Y, Matsumura T, Furusho K

Abstract excerpt

Mutant frequencies (Mfs) at the two genetic loci, the hypoxanthine phosphoribosyl transferase (hprt) gene and the T-cell receptor (TCR) gene were evaluated in pediatric cancer patients before starting chemotherapy or radiotherapy. The study population consisted of 27 patients with various solid t...

Topics

Adolescent
Child
Child, Preschool
Female
Humans
Hypoxanthine Phosphoribosyltransferase
Male
Mutation
Neoplasms
Receptors, Antigen, T-Cell

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