Article
Evaluation of mutant frequencies at the hprt and the T-cell receptor loci in pediatric cancer patients before treatment.
Mutation research - 2 Feb 1998
Sawada M, Kubota M, Lin Y W, Watanabe K, Koishi S, Usami I, Akiyama Y, Matsumura T, Furusho K
Abstract excerpt
Mutant frequencies (Mfs) at the two genetic loci, the hypoxanthine phosphoribosyl transferase (hprt) gene and the T-cell receptor (TCR) gene were evaluated in pediatric cancer patients before starting chemotherapy or radiotherapy. The study population consisted of 27 patients with various solid tumors (mean age +/- SD; 5.5 +/- 5.1 years, range; 0.2-14.5 years), 5 patients with acute leukemia (10.3 +/- 6.1,...
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