Article
Transcription-coupled and splicing-coupled strand asymmetries in eukaryotic genomes.
Nucleic acids research - 1 Jan 2004
Touchon Marie, Arneodo Alain, d'Aubenton-Carafa Yves, Thermes Claude
Abstract excerpt
Under no-strand bias conditions, each genomic DNA strand should present equimolarities of A and T and of G and C. Deviations from these rules are attributed to asymmetric properties intrinsic to DNA mutation-repair processes. In bacteria, strand biases are associated with replication or transcription. In eukaryotes, recent studies demonstrate that human genes present transcription-coupled biases that might...
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