Article
Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences.
Nucleic acids research - 11 Jan 2021
Georgakopoulos-Soares Ilias, Mouratidis Ioannis, Parada Guillermo E, Matharu Navneet, Hemberg Martin, Ahituv Nadav
Abstract excerpt
DNA strand asymmetries can have a major effect on several biological functions, including replication, transcription and transcription factor binding. As such, DNA strand asymmetries and mutational strand bias can provide information about biological function. However, a versatile tool to explore this does not exist. Here, we present Asymmetron, a user-friendly computational tool that performs statistical...
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