Article
Strand compositional asymmetries of nuclear DNA in eukaryotes.
Journal of molecular evolution - 1 Sept 2003
Niu Deng K, Lin Kui, Zhang Da-Yong
Abstract excerpt
Both DNA replication and transcription are structurally asymmetric processes. An asymmetric nucleotide substitution pattern has been observed between the leading and the lagging strand, and between the coding and the noncoding strand, in eubacterial, viral, and organelle genomes. Similar studies in eukaryotes have been rare, because the origins of replication in nuclear genomes are mostly unknown and the...
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