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Article

High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana.

European journal of clinical pharmacology - 1 Feb 2005

Gyamfi Maxwell Afari, Fujieda Masaki, Kiyotani Kazuma, Yamazaki Hiroshi, Kamataki Tetsuya

Abstract excerpt

OBJECTIVE: We investigated the frequencies of the functionally important variants of the CYP2A6 gene in black African populations. METHODS: Using genomic DNA sequencing, polymerase chain reaction (PCR)-restriction fragment length polymorphism and allele-specific PCR, the allele frequencies of CYP2A6 *1A, *1B, *2, *4A, *5, *6, *7, *8, *9, *10 and * 11 among 120 black Africans- including 105 Ghanaians, 12...

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PMID: 15660270
DOI: 10.1007/s00228-004-0854-9

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