Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans.

Clinical chemistry and laboratory medicine - 1 Sept 2002

Dandara Collet, Sayi Jane, Masimirembwa Collen M, Magimba Ayoub, Kaaya Sylvia, De Sommers Kierk, Snyman Jacques René, Hasler Julia A

Abstract excerpt

The co-ordinate expression and regulation of the drug metabolising enzymes, cytochrome P4501A1 (CYPlAl) and glutathione transferases (GSTM1, GSTT1 and GSTP1), and their metabolic balance in the cells of target organs may determine whether exposure to carcinogens results in cancer. Besides showing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa
Share to Cytochrome P-450 CYP1A1
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Isoenzymes

Share to Mental Disorders

Share to Point Mutation

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 12435115
DOI: 10.1515/CCLM.2002.167

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12435115-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans.PMID 12435115Read ↗

Genetic polymorphism of drug metabolism enzymes (GSTM1, GSTT1 and GSTP1) in the healthy Malian population.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P4501A1, microsomal epoxide hydrolase, and glutathione S-transferases M1 and T1 in Zimbabweans and Venda of southern Africa.Semantic proximity Read ↗

Frequencies of GSTM1, GSTT1, and GSTP1 polymorphisms in a Brazilian population.Semantic proximity Read ↗

Frequency of glutathione-S-transferase null-M1 and null-T1 genotypes among the Turabah population in Saudi Arabia.Semantic proximity Read ↗

Allelic variation of GSTT1, GSTM1 and GSTP1 genes in North Indian population.Semantic proximity Read ↗

Polymorphic expression of glutathione transferases A1, M1, P1 and T1 in epithelial ovarian cancer: a Serbian case-control study.Semantic proximity Read ↗

Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus.Semantic proximity Read ↗

Cytochrome P450 1A1, glutathione S-transferases M1 and T1 polymorphisms in Ovambos and Mongolians.Semantic proximity Read ↗

GSTT1 and GSTM1 gene polymorphisms in European and African populations.Semantic proximity Read ↗

Polymorphisms of glutathione-S-transferase M1 and T1 and prostate cancer risk in a Tunisian population.Semantic proximity Read ↗

Polymorphic variation within the glutathione S-transferase genes and risk of adult acute leukaemia.Semantic proximity Read ↗

Identification of the GST-T1 and GST-M1 null genotypes using high resolution melting analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.