Article
CYP1A2 polymorphism (C > A at position -163) in Ovambos, Koreans and Mongolians.
Cell biochemistry and function - 1 Jan 2000
Fujihara Junko, Shiwaku Kuninori, Xue Yuing, Kataoka Kaori, Hieda Yoko, Takeshita Haruo
Abstract excerpt
Cytochrome P450 1A2 (CYP1A2) plays an important role in metabolizing drugs and xenobiotics, and is a possible participant in the development of several human diseases. Recent studies have shown that genetic polymorphism of -163 C > A single nucleotide mutation of CYP1A2 increases the risk of myocardial infarction and modulates CYP1A2 activity. In this study, we investigated the frequency of the -163 C > A...
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